Metagenomic analysis of intestinal microbiota samples from IBD patients; Meta-analysis of multi-omics data to explore the impact of different food additives on the occurrence of IBD; Assembly and functional annotation of eukaryotic genome sequences; Homologous sequence analysis and functional prediction of protein sequences.

Built an Oxford Nanopore sequencing experimental platform and established a bioinformatics analysis pipeline; Participated in the development of a novel diagnostic kit, contributing to the design and manufacture of sample pre-treatment procedures; Mined public genetic databases using pan-genome analysis tools, identifying a series of bio-marker gene sequences for the molecular detection of pathogenic microorganisms, such as Mycobacterium tuberculosis. Applied Deep learning based model(ResUNet, Transformer) to Raman signal denoising and classcification for clinical application and AMR diagnosis. Developed a label-free, Raman single-cell sorting and sequencing system for versatile applications in industry and clinical diagnosis. Proactively solve problems and move research projects (and/or new technologies) forward.